Description

(R)-B-Amino-3-Fluorobenzenepropanol is a chiral, fluorinated amino alcohol building block of significant importance in modern synthetic chemistry. Its unique structure, featuring both an amino group and a fluorine atom on an aromatic ring, makes it a versatile intermediate for constructing complex molecules with tailored biological activity. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries. It serves as a critical precursor for the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals where stereochemistry and fluorine substitution are key design elements.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the fluorine atom enhances bioavailability and metabolic stability.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands for asymmetric catalysis, enabling the synthesis of enantiomerically pure compounds.
• Peptidomimetics and Bioactive Molecules: Serves as a building block for non-natural amino acids and other complex structures in medicinal chemistry programs.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with unique properties.
• Academic and Industrial R&D: A valuable tool for chemical biology studies and process chemistry optimization in laboratory-scale and pilot-scale operations.

Basic Information

Product Name	(R)-B-Amino-3-Fluorobenzenepropanol
CAS No.	774243-59-3
Molecular Formula	C9H12FNO
Molecular Weight	169.20 g/mol
Synonyms	(R)-3-Amino-3-(3-fluorophenyl)-1-propanol; (R)-3-Amino-3-(3-fluorophenyl)propan-1-ol; (R)-β-Amino-3-fluorobenzenepropanol; (3R)-3-Amino-3-(3-fluorophenyl)-1-propanol; (R)-3-Fluoro-β-aminobenzenepropanol; Benzenepropanol, β-amino-3-fluoro-, (βR)-; (R)-1-(3-Aminopropyl)-3-fluorobenzene
EINECS	Contact for details

Quality Control

Our (R)-B-Amino-3-Fluorobenzenepropanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity (typically >98%), enantiomeric excess (typically >99% ee), and impurity profiles are available upon request. We support compliance with relevant guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.