Description

2,3-Difluoro-6-Methoxybenzoic Acid Methyl Ester is a high-value fluorinated aromatic building block essential for advanced organic synthesis. This compound is critical for introducing specific fluorine-substituted benzoate motifs into target molecules, which can significantly alter their electronic properties, metabolic stability, and binding affinity. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients, particularly in medicinal chemistry programs targeting kinase inhibitors and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, especially those requiring fluorinated aromatic systems for enhanced bioactivity and ADME properties.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the difluoro-methoxybenzoate structure contributes to efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for display technologies.
• Organic Electronic Materials: Employed in the development of organic semiconductors and charge-transport materials due to its tunable electronic characteristics.
• Chemical Research & Development: A versatile building block for constructing complex, fluorinated molecules in academic and industrial R&D settings.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for use in custom synthesis projects and scale-up campaigns for client-specific molecules.

Basic Information

Product Name	2,3-Difluoro-6-Methoxybenzoic Acid Methyl Ester
CAS No.	773876-05-4
Molecular Formula	C10H8F2O3
Molecular Weight	214.16 g/mol
Synonyms	Methyl 2,3-difluoro-6-methoxybenzoate; 2,3-Difluoro-6-methoxybenzoic acid methyl ester; Benzoic acid, 2,3-difluoro-6-methoxy-, methyl ester; 6-Methoxy-2,3-difluorobenzoic acid methyl ester; Methyl 6-methoxy-2,3-difluorobenzoate
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-6-Methoxybenzoic Acid Methyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data with each shipment. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request and are standard for all commercial orders.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.