Description

Methyl 2,3-Difluoro-4-Methylbenzoate is a high-purity fluorinated aromatic ester, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms and the methyl ester group, which are essential for modulating the electronic and steric properties of target molecules. This compound is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for developing new active ingredients, particularly in the creation of complex heterocycles and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the difluoro motif enhances biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for advanced display technologies.
• Organic Electronic Materials: Employed in the research and production of materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Research & Development: A versatile reagent for introducing the 2,3-difluoro-4-methylbenzoyl moiety into more complex molecular architectures.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the scale-up and production of proprietary compounds under cGMP guidelines where applicable.

Basic Information

Product Name	Methyl 2,3-Difluoro-4-Methylbenzoate
CAS No.	773874-06-9
Molecular Formula	C9H8F2O2
Molecular Weight	186.16 g/mol
Synonyms	2,3-Difluoro-4-methylbenzoic acid methyl ester; Methyl 2,3-difluoro-p-toluate; Benzoic acid, 2,3-difluoro-4-methyl-, methyl ester; 4-Methyl-2,3-difluorobenzoic acid methyl ester; 2,3-Difluoro-4-methyl methylbenzoate; Methyl 2,3-difluoro-4-methylbenzenecarboxylate
EINECS	Contact for details

Quality Control

Our Methyl 2,3-Difluoro-4-Methylbenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment. We adhere to relevant ISO standards and can support development under ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.