Description

Methyl 6-Chloro-2-Fluoro-3-Methylbenzoate is a high-purity fluorinated benzoate ester, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its precise molecular architecture, which enables the efficient construction of complex molecules for demanding applications. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides and fungicides, where the chloro-fluoro substitution pattern is valuable for bioactivity.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and liquid crystals with unique optical or electronic properties.
• Chemical Biology: Employed as a probe or labeling reagent in medicinal chemistry for structure-activity relationship (SAR) studies.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	Methyl 6-Chloro-2-Fluoro-3-Methylbenzoate
CAS No.	773874-01-4
Molecular Formula	C9H8ClFO2
Molecular Weight	202.61 g/mol
Synonyms	6-Chloro-2-fluoro-3-methylbenzoic acid methyl ester; Methyl 6-chloro-2-fluoro-m-toluate; Benzoic acid, 6-chloro-2-fluoro-3-methyl-, methyl ester; 2-Fluoro-6-chloro-3-methylbenzoic acid methyl ester; 3-Methyl-6-chloro-2-fluorobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 6-Chloro-2-Fluoro-3-Methylbenzoate adheres to stringent in-process controls and final batch analysis to ensure consistent high purity and identity. Every lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics. We operate under a quality management system and can supply material compliant with cGMP standards for pharmaceutical development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.