Description

Methyl 3-Fluoro-4-Trifluoromethylbenzoate is a high-purity fluorinated aromatic ester building block of significant importance in advanced organic synthesis. This compound is valued for its role in introducing both fluorine and trifluoromethyl substituents, which are critical for modulating the physicochemical properties of target molecules. It is primarily sought after by R&D and process chemistry teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance display technologies.
• Polymer Chemistry: Employed as a monomer or modifier to create specialty polymers with improved chemical resistance, thermal stability, and surface properties.
• Organic Electronic Materials: Utilized in the development of electron-transport materials and semiconductors for OLEDs and organic photovoltaics.
• Chemical Research: Acts as a versatile building block in medicinal chemistry and material science research for structure-activity relationship (SAR) studies.

Basic Information

Product Name	Methyl 3-Fluoro-4-Trifluoromethylbenzoate
CAS No.	773873-89-5
Molecular Formula	C9H6F4O2
Molecular Weight	222.14 g/mol
Synonyms	3-Fluoro-4-(trifluoromethyl)benzoic Acid Methyl Ester; Methyl 3-Fluoro-α,α,α-trifluoro-p-toluate; Benzoic acid, 3-fluoro-4-(trifluoromethyl)-, methyl ester; Methyl 3-Fluoro-4-trifluoromethylbenzoate; 4-(Trifluoromethyl)-3-fluorobenzoic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Fluoro-4-Trifluoromethylbenzoate adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including GC, HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.