Description

Methyl 2,3,5-Trifluorobenzoate CAS NO 773873-73-7 is a high-purity fluorinated aromatic ester, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in the strategic placement of fluorine atoms on the benzoate ring, which imparts unique electronic and steric properties essential for constructing complex molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as by manufacturers of specialty materials and liquid crystals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl benzoate moiety enhances biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for high-performance displays (LCDs).
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and as a substrate for further functionalization in medicinal chemistry research.
• Specialty Polymer Modifier: Acts as a monomer or additive to introduce fluorine into polymer chains, improving chemical resistance and surface properties.
• Chemical Research & Development: A valuable tool for academic and industrial labs exploring new fluorination methodologies and structure-activity relationships.

Basic Information

Product Name	Methyl 2,3,5-Trifluorobenzoate
CAS No.	773873-73-7
Molecular Formula	C8H5F3O2
Molecular Weight	190.12 g/mol
Synonyms	2,3,5-Trifluorobenzoic Acid Methyl Ester; Methyl 2,3,5-Trifluorobenzoate; Benzoic Acid, 2,3,5-Trifluoro-, Methyl Ester; Methyl 2,3,5-Trifluorobenzenecarboxylate; 2,3,5-Trifluorobenzenecarboxylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our Methyl 2,3,5-Trifluorobenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed and stored under an inert atmosphere if prolonged storage is required.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (by GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.