Description

Methyl 3,4,5-Trifluorobenzenecarboxylate is a high-purity fluorinated aromatic ester, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the strategic placement of fluorine atoms on the aromatic ring, which significantly influences the electronic and physical properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to build complex active ingredients requiring enhanced metabolic stability, bioavailability, and lipophilicity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting the central nervous system, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl benzoate moiety contributes to improved efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for high-performance displays (LCDs).
• Organic Electronics: Acts as a monomer or intermediate in the synthesis of semiconductors and charge-transport materials for OLEDs and organic photovoltaics.
• Chemical Research & Development: A versatile reagent for introducing the 3,4,5-trifluorophenyl group into complex molecular architectures in medicinal and materials chemistry.
• Fluorine Chemistry Studies: Used as a model compound for investigating reaction mechanisms and developing new fluorination methodologies.

Basic Information

Product Name	Methyl 3,4,5-Trifluorobenzenecarboxylate
CAS No.	773873-72-6
Molecular Formula	C8H5F3O2
Molecular Weight	190.12 g/mol
Synonyms	Methyl 3,4,5-Trifluorobenzoate; 3,4,5-Trifluorobenzoic Acid Methyl Ester; Benzoic acid, 3,4,5-trifluoro-, methyl ester; Methyl 3,4,5-Trifluorobenzoate; Methyl 3,4,5-Trifluorophenylcarboxylate; 3,4,5-Trifluoromethyl Benzoate; MFCD 1111 (example placeholder, contact for specific ID)
EINECS	Contact for details

Quality Control

Our Methyl 3,4,5-Trifluorobenzenecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable consistency and traceability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and potential decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.