Description

3-Chloro-2-Fluorobenzoic Acid Ethyl Ester is a high-purity fluorinated benzoate ester derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the strategic positioning of halogen substituents, which enable precise functionalization for creating complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring halogenated aromatic cores for bioactivity.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine and chlorine atoms enhance compound stability and efficacy.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Organic Synthesis & Chemical Research: A versatile reagent for coupling reactions, esterifications, and as a protected form of the corresponding carboxylic acid in multi-step syntheses.
• Fluorine Chemistry Studies: Valuable substrate for investigating the effects of ortho-substituted fluorine atoms on reaction kinetics and regioselectivity.

Basic Information

Product Name	3-Chloro-2-Fluorobenzoic Acid Ethyl Ester
CAS No.	773135-55-0
Molecular Formula	C9H8ClFO2
Molecular Weight	202.61 g/mol
Synonyms	Ethyl 3-Chloro-2-fluorobenzoate; 3-Chloro-2-fluorobenzoic Acid Ethyl Ester; Benzoic acid, 3-chloro-2-fluoro-, ethyl ester; 2-Fluoro-3-chlorobenzoic Acid Ethyl Ester; Ethyl 2-Fluoro-3-chlorobenzoate; 773135-55-0; Ester of 3-Chloro-2-fluorobenzoic Acid
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-2-Fluorobenzoic Acid Ethyl Ester adheres to stringent in-process controls and final batch testing to ensure consistent high purity and reliable performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system supports compliance with cGMP and ISO standards for traceability and reproducibility, making this material suitable for demanding R&D and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.