Description

Ethyl 3-Fluoro-4-(Trifluoromethyl)Benzoate is a high-purity fluorinated aromatic ester building block, essential for introducing specific fluorine-substituted motifs into target molecules. Its value lies in enabling the synthesis of advanced materials and active pharmaceutical ingredients (APIs) with tailored electronic and steric properties. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel drug candidates, particularly for CNS and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides where the trifluoromethyl group enhances biological activity.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated components in electronic display and lighting materials.
• Polymer Modification: Incorporated into specialty polymers to alter solubility, thermal stability, and chemical resistance.
• Cross-Coupling Reactions: Utilized in Suzuki, Stille, or other palladium-catalyzed coupling reactions to construct complex biaryl systems.
• Chemical Research & Development: A versatile reagent for exploring new fluorination strategies and creating compound libraries for screening.

Basic Information

Product Name	Ethyl 3-Fluoro-4-(Trifluoromethyl)Benzoate
CAS No.	773135-31-2
Molecular Formula	C10H8F4O2
Molecular Weight	236.16 g/mol
Synonyms	Ethyl 3-Fluoro-4-(trifluoromethyl)benzoate; Benzoic acid, 3-fluoro-4-(trifluoromethyl)-, ethyl ester; 3-Fluoro-4-(trifluoromethyl)benzoic Acid Ethyl Ester; Ethyl 3-Fluoro-α,α,α-trifluoro-p-toluate; 773135-31-2; Ethyl 3-Fluoro-4-trifluoromethylbenzoate
EINECS	Contact for details

Quality Control

Our Ethyl 3-Fluoro-4-(Trifluoromethyl)Benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids, organic solvents, fluorides, and strong alkalis. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.