Description

5-Fluoro-2-Methoxybenzoic Acid Ethyl Ester is a high-purity fluorinated aromatic ester building block of significant importance in advanced organic synthesis. This compound serves as a critical intermediate for the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique substitution pattern enables precise molecular modifications. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic components used in electronic display technologies.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, esterifications, and other transformations to introduce the 5-fluoro-2-methoxybenzoate moiety into complex molecules.
• Chemical Research & Development: Essential for academic and industrial R&D exploring new fluorinated compounds and their properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on various scales.

Basic Information

Product Name	5-Fluoro-2-Methoxybenzoic Acid Ethyl Ester
CAS No.	773135-09-4
Molecular Formula	C10H11FO3
Molecular Weight	198.19 g/mol
Synonyms	Ethyl 5-Fluoro-2-methoxybenzoate; 5-Fluoro-2-methoxybenzoic Acid Ethyl Ester; 2-Methoxy-5-fluorobenzoic Acid Ethyl Ester; Benzoic acid, 5-fluoro-2-methoxy-, ethyl ester; Ethyl 5-fluoro-o-anisate
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Methoxybenzoic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP standards where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0% (Typical 99.0%)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.