Description

2-Fluoro-5-Trifluoromethylbenzoic Acid Ethyl Ester is a high-value fluorinated aromatic building block essential for advanced organic synthesis. This compound is prized for its ability to introduce both fluorine and trifluoromethyl groups, which are critical for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and antiviral drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the fluorine and trifluoromethyl groups enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance displays.
• Organic Electronics: Employed in the development of novel organic semiconductors and electron-transport materials.
• Cross-Coupling Reactions: Acts as a versatile substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial research exploring new methodologies in fluoroorganic chemistry.

Basic Information

Product Name	2-Fluoro-5-Trifluoromethylbenzoic Acid Ethyl Ester
CAS No.	773134-94-4
Molecular Formula	C10H8F4O2
Molecular Weight	236.16 g/mol
Synonyms	Ethyl 2-Fluoro-5-(trifluoromethyl)benzoate; Benzoic acid, 2-fluoro-5-(trifluoromethyl)-, ethyl ester; 2-Fluoro-α,α,α-trifluoro-m-toluic acid ethyl ester; Ethyl 2-fluoro-α,α,α-trifluoro-m-toluate; 2-Fluoro-5-trifluoromethylbenzoic acid ethyl ester; Ethyl 2-fluoro-5-trifluoromethylbenzoate; m-Trifluoromethyl-2-fluorobenzoic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Trifluoromethylbenzoic Acid Ethyl Ester is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for research and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.