Description

Methyl 4-Bromo-2,6-Difluorobenzoate is a high-purity, multi-functional aromatic ester building block essential for advanced organic synthesis. Its core value lies in its unique halogenated difluorobenzene structure, which provides a versatile platform for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing difluorophenyl motifs, which are common in drug discovery.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of halogenated aromatic compounds.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the creation of advanced organic materials, such as liquid crystals and polymers, where fluorinated aromatic units enhance stability and performance.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	Methyl 4-Bromo-2,6-Difluorobenzoate
CAS No.	773134-11-5
Molecular Formula	C8H5BrF2O2
Molecular Weight	251.03 g/mol
Synonyms	4-Bromo-2,6-difluorobenzoic acid methyl ester; Methyl 4-bromo-2,6-difluorobenzoate; Benzoic acid, 4-bromo-2,6-difluoro-, methyl ester; 2,6-Difluoro-4-bromobenzoic acid methyl ester; Methyl 4-bromo-2,6-difluorobenzoate; 773134-11-5; Methyl ester of 4-bromo-2,6-difluorobenzoic acid
EINECS	Contact for details

Quality Control

Our Methyl 4-Bromo-2,6-Difluorobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Melting Point	Contact for details
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.