Description

Methyl 2,4-Dibromo-6-Fluorobenzoate is a high-purity fluorinated and brominated aromatic ester, serving as a critical advanced intermediate in modern organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries seeking to introduce halogenated motifs for bioactivity or material properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides and fungicides, where the fluorine and bromine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic cores in electronic materials, contributing to improved performance in display and lighting technologies.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the presence of bromine substituents.
• Chemical Research & Development: A versatile reagent for academic and industrial research exploring new fluorination methodologies and heterocyclic chemistry.
• Specialty Polymer Modifier: Can be incorporated as a monomer to introduce halogenated aromatic units into polymers, altering thermal and optical properties.

Basic Information

Product Name	Methyl 2,4-Dibromo-6-Fluorobenzoate
CAS No.	773134-10-4
Molecular Formula	C8H5Br2FO2
Molecular Weight	311.93 g/mol
Synonyms	2,4-Dibromo-6-fluorobenzoic acid methyl ester; Methyl 2,4-dibromo-6-fluorobenzoate; Benzoic acid, 2,4-dibromo-6-fluoro-, methyl ester; 6-Fluoro-2,4-dibromobenzoic acid methyl ester; Methyl 6-fluoro-2,4-dibromobenzoate
EINECS	Contact for details

Quality Control

Every batch of Methyl 2,4-Dibromo-6-Fluorobenzoate is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and high purity. Our standard quality commitment includes comprehensive analysis by HPLC, GC, NMR, and MS to confirm identity and quantify purity and impurity profiles. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment, and we support customer audits and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere such as nitrogen for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.