Description

2-Fluoro-5-Methylcinnamic Acid is a high-purity fluorinated cinnamic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a fluorine atom and a methyl group on the aromatic ring, makes it a valuable synthon for creating complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, including potential kinase inhibitors and anti-inflammatory agents.
• Agrochemical Research: Used to develop novel pesticides and herbicides, where the fluorine atom can enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated aromatic cores in electronic materials, improving charge transport and thermal stability.
• Chemical Biology Probes: Employed in the design of fluorinated probes and tags for studying biological processes and protein interactions.
• Polymer Modification: Acts as a monomer or cross-linking agent for introducing fluorinated aromatic units into specialty polymers.
• Academic & R&D: A versatile reagent for methodological development in organic chemistry, particularly in cross-coupling and fluorination reactions.

Basic Information

Product Name	2-Fluoro-5-Methylcinnamic Acid
CAS No.	773130-21-5
Molecular Formula	C10H9FO2
Molecular Weight	180.18 g/mol
Synonyms	(2E)-3-(2-Fluoro-5-methylphenyl)acrylic acid; (E)-3-(2-Fluoro-5-methylphenyl)acrylic acid; trans-2-Fluoro-5-methylcinnamic acid; 2-Fluoro-5-methyl-trans-cinnamic acid; 3-(2-Fluoro-5-methylphenyl)-2-propenoic acid; 2-Fluoro-5-methylcinnamate; 2-Fluoro-5-methylbenzeneacrylic acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Methylcinnamic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with all shipments, detailing batch-specific results. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.