Description

2,4-Bis(Trifluoromethyl)Cinnamicacid is a high-value fluorinated organic building block characterized by its cinnamic acid core substituted with two trifluoromethyl groups. This compound matters for its role as a key intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where the introduction of fluorine atoms is critical for modulating properties like metabolic stability and lipophilicity. It is needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel compounds with enhanced performance characteristics.

Application

• Pharmaceutical intermediate for the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Key building block in agrochemical research for creating new herbicides and pesticides with improved efficacy.
• Precursor for advanced materials, including liquid crystals and organic semiconductors for electronic applications.
• Intermediate in the development of specialty dyes and pigments with unique optical properties.
• Research chemical for academic and industrial studies in fluorination chemistry and structure-activity relationships (SAR).
• Starting material for the synthesis of complex ligands used in catalysis and material science.

Basic Information

Product Name	2,4-Bis(Trifluoromethyl)Cinnamicacid
CAS No.	773129-10-5
Molecular Formula	C₁₂H₆F₆O₂
Molecular Weight	296.17 g/mol
Synonyms	(E)-3-[2,4-Bis(trifluoromethyl)phenyl]acrylic acid; 2,4-Bis(trifluoromethyl)cinnamic acid; (E)-3-(2,4-Bis(trifluoromethyl)phenyl)-2-propenoic acid; α,2,4-Bis(trifluoromethyl)cinnamic acid; trans-2,4-Bis(trifluoromethyl)cinnamic acid; 3-(2,4-Bis(trifluoromethyl)phenyl)prop-2-enoic acid
EINECS	Contact for details

Quality Control

Our 2,4-Bis(Trifluoromethyl)Cinnamicacid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.