Description

Vilazodone Dihydrochloride CAS NO 765936-04-7 is the dihydrochloride salt form of Vilazodone, a potent and selective serotonin reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist. This high-purity active pharmaceutical ingredient (API) is critical for ensuring the efficacy and consistency of finished pharmaceutical formulations. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of antidepressant medications.

Application

• Pharmaceutical API: Primary active ingredient in the manufacture of antidepressant tablets and capsules.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for quality control and method validation.
• Clinical Research: Serves as a key material in preclinical and clinical studies for new therapeutic formulations.
• Generic Drug Development: Essential for companies developing bioequivalent versions of branded antidepressant drugs.
• Process Development & Scale-up: Used in R&D for optimizing synthesis and purification processes.

Basic Information

Product Name	Vilazodone Dihydrochloride
CAS No.	765936-04-7
Molecular Formula	C26H28Cl2N5O2
Molecular Weight	521.44 g/mol
Synonyms	Vilazodone HCl; 5-[4-[4-(5-Cyano-1H-indol-3-yl)butyl]piperazin-1-yl]benzofuran-2-carboxamide dihydrochloride; SB-659746A; Viibryd (Trade Name) API; EMD-68843; Vilazodone (free base); Vilazodone Dihydrochloride Salt
EINECS	Contact for details

Quality Control

Our Vilazodone Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and impurity profiles, aligning with ICH guidelines. A Certificate of Analysis (COA) detailing results for assay, related substances, residual solvents, and other critical parameters is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.