Description

3-Fluoro-2,4-Dimethylphenylboronic Acid is a high-purity organoboron compound, specifically a boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality reagents for developing active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in constructing advanced herbicide and pesticide molecules, where the fluorine and dimethyl substitutions can enhance biological activity and environmental stability.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and organic semiconductors, where precise molecular structure controls optoelectronic properties.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and other transition metal-catalyzed processes.
• Chemical Biology & Proteomics: Utilized in the synthesis of molecular probes and activity-based protein profiling (ABPP) reagents that leverage boronic acid chemistry for selective binding.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex, tailor-made organic compounds for clients.

Basic Information

Product Name	3-Fluoro-2,4-Dimethylphenylboronic Acid
CAS No.	762286-31-7
Molecular Formula	C8H10BFO2
Molecular Weight	167.98 g/mol
Synonyms	(3-Fluoro-2,4-dimethylphenyl)boronic acid; 2,4-Dimethyl-3-fluorophenylboronic acid; 3-Fluoro-2,4-dimethylbenzeneboronic acid; Boronic acid, B-(3-fluoro-2,4-dimethylphenyl)-; 762286-31-7; 3-Fluoro-2,4-DMBPA
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2,4-Dimethylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for sensitive cross-coupling reactions. A detailed Certificate of Analysis (COA) with full traceability is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (argon or nitrogen) for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.