Description

1-Azabicyclo[2.2.2]Octane-2-Carboxylicacid,(R)-(9Ci) is a high-purity, chiral bicyclic amino acid derivative of significant interest in advanced organic synthesis. This compound serves as a critical building block for the development of novel pharmaceuticals and complex molecular architectures. It is primarily utilized by research institutions and industrial R&D departments focused on medicinal chemistry, asymmetric synthesis, and the creation of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for neurological and metabolic disorders.
• Asymmetric Catalyst Ligand Precursor: Used to synthesize sophisticated ligands for metal-catalyzed asymmetric reactions, enhancing enantioselectivity.
• Peptidomimetics & Constrained Peptide Design: Incorporates rigid, three-dimensional structural elements into peptide backbones to improve stability and bioavailability.
• Academic & Industrial Research: Serves as a valuable reagent for methodological studies in organic chemistry and novel heterocycle construction.
• Agrochemical Synthesis: Potential intermediate in the development of advanced, enantiomerically pure crop protection agents.

Basic Information

Product Name	1-Azabicyclo[2.2.2]Octane-2-Carboxylicacid,(R)-(9Ci)
CAS No.	757899-36-8
Molecular Formula	C8H13NO2
Molecular Weight	155.19 g/mol
Synonyms	(R)-1-Azabicyclo[2.2.2]octane-2-carboxylic acid; (R)-Quinuclidine-2-carboxylic acid; (2R)-2-Quinuclidinecarboxylic acid; (R)-2-Quinuclidinecarboxylic Acid; (R)-Quinuclidine-2-Carboxylic Acid; (R)-1-Azabicyclo[2.2.2]octane-2-carboxylic acid hydrochloride (salt forms); (R)-QCA
EINECS	Contact for details

Quality Control

Our 1-Azabicyclo[2.2.2]Octane-2-Carboxylicacid,(R)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.