Description

6-Benzothiazolol-2-14C, 5,7-Dimethyl-2-(Methylamino)-4-(3-Pyridinylmethyl)- (9Ci) is a specialized, isotopically labeled benzothiazole derivative of significant interest in pharmaceutical and agrochemical research. This compound is primarily valued as a critical intermediate or reference standard in the development and metabolic study of novel active ingredients. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors who require high-purity, structurally complex building blocks for drug discovery, process development, and analytical method validation.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate in the synthesis of novel drug candidates, particularly those targeting neurological or oncological pathways.
• Metabolic Pathway Tracing: The 14C isotopic label enables precise tracking of the compound's absorption, distribution, metabolism, and excretion (ADME) in biological systems.
• Agrochemical Discovery: Used in the research and development of new pesticides or herbicides, leveraging the benzothiazole scaffold's bioactivity.
• Analytical Reference Standard: Provides a certified material for quality control (QC) and method development in HPLC, LC-MS, or NMR analysis.
• Chemical Biology Probes: Utilized in the design of molecular probes to study enzyme function or protein-ligand interactions.
• Process Chemistry & Scale-up: Acts as a critical building block during the optimization and pilot-scale production of active pharmaceutical ingredients (APIs).

Basic Information

Item	Details
Product Name	6-Benzothiazolol-2-14C, 5,7-Dimethyl-2-(Methylamino)-4-(3-Pyridinylmethyl)- (9Ci)
CAS No.	756452-46-7
Molecular Formula	C₁₆H₁₇N₃OS (with 14C label at position 2)
Molecular Weight	~299.39 g/mol (unlabeled)
Synonyms	5,7-Dimethyl-2-(methylamino)-4-(pyridin-3-ylmethyl)-1,3-benzothiazol-6-ol-2-14C; 2-14C-Labeled 6-Benzothiazolol Derivative; [2-14C]-5,7-Dimethyl-2-(methylamino)-4-(3-pyridinylmethyl)benzothiazol-6-ol; Benzothiazole-2-14C Intermediate; 756452-46-7 (9Ci); Research Compound 756452-46-7
EINECS	Contact for details

Quality Control

Every batch of 6-Benzothiazolol-2-14C, 5,7-Dimethyl-2-(Methylamino)-4-(3-Pyridinylmethyl)- (9Ci) is manufactured and analyzed under strict quality management systems. We provide comprehensive analytical data including HPLC purity, radiochemical purity, and specific activity to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept in a desiccated environment. For long-term stability, consider storage under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Radiochemical Purity	≥ 97.0%
Specific Activity	Customizable (mCi/mmol)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.