Description

Benzoic Acid, 5-Methyl-2-[[3-(Trifluoromethyl)Phenyl]Amino]- is a specialized trifluoromethyl-substituted aniline derivative of benzoic acid, offering a unique combination of aromatic and fluorinated properties. This compound is valued for its role as a key synthetic intermediate in advanced organic synthesis, particularly in the development of active pharmaceutical ingredients and agrochemicals. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating novel molecules with enhanced biological activity and stability.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, due to the trifluoromethyl group's ability to modulate pharmacokinetic properties.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to improved lipophilicity and metabolic stability.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Employed as a standard or reagent in methodological studies for new amination, fluorination, or coupling reactions in academic and industrial R&D labs.
• Dye and Pigment Intermediate: Utilized in the synthesis of complex organic dyes and pigments, where the aniline and benzoic acid moieties provide chromophoric and binding properties.

Basic Information

Product Name	Benzoic Acid, 5-Methyl-2-[[3-(Trifluoromethyl)Phenyl]Amino]-
CAS No.	744149-01-7
Molecular Formula	C15H12F3NO2
Molecular Weight	295.26 g/mol
Synonyms	2-[[3-(Trifluoromethyl)phenyl]amino]-5-methylbenzoic acid; 5-Methyl-2-((3-(trifluoromethyl)phenyl)amino)benzoic acid; N-[3-(Trifluoromethyl)phenyl]-5-methylanthranilic acid; 2-Amino-5-methylbenzoic acid 3-trifluoromethylphenyl derivative; α-Amino-m-toluic acid N-(3-trifluoromethylphenyl) derivative; Benzoic acid, 2-[[3-(trifluoromethyl)phenyl]amino]-5-methyl-; 744149-01-7
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 5-Methyl-2-[[3-(Trifluoromethyl)Phenyl]Amino]- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay (HPLC), identification (IR, NMR), and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.