Description

Benzenebutanoic Acid, 2-Fluoro-α,γ-Dioxo-, Ethyl Ester is a specialized fluorinated keto-ester building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where the introduction of fluorine atoms is a critical strategy for modulating biological activity and metabolic stability. It is primarily needed by research chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), crop protection agents, and other high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing fluorinated drug candidates, especially in oncology, CNS, and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where fluorine substitution enhances efficacy and environmental profile.
• Material Science Research: Serves as a precursor for novel fluorinated polymers or liquid crystals with unique thermal and optical properties.
• Chemical Biology Probes: Employed in the design of fluorinated probes and tags for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific molecule production.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry, particularly in cross-coupling and condensation reactions.

Basic Information

Item	Detail
Product Name	Benzenebutanoic Acid, 2-Fluoro-α,γ-Dioxo-, Ethyl Ester
CAS No.	741286-80-6
Molecular Formula	C12H11FO4
Molecular Weight	238.21 g/mol
Synonyms	Ethyl 2-Fluoro-α,γ-dioxobenzenebutanoate; 2-Fluoro-α,γ-dioxobenzenebutanoic Acid Ethyl Ester; Ethyl 4-(2-Fluorophenyl)-2,4-dioxobutanoate; 4-(2-Fluorophenyl)-2,4-dioxobutanoic Acid Ethyl Ester; 2-Fluoro-α,γ-dioxo-benzenebutanoic Acid Ethyl Ester; Butanoic acid, 4-(2-fluorophenyl)-2,4-dioxo-, ethyl ester; 741286-80-6
EINECS	Contact for details

Quality Control

Our Benzenebutanoic Acid, 2-Fluoro-α,γ-Dioxo-, Ethyl Ester is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our commitment to quality supports your R&D and scale-up processes with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.