Description

Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, 2-Amino-3-Hydroxy-, (1R,2S,3R,4S)-Rel- (9Ci) is a high-purity, stereochemically defined bicyclic amino acid derivative that serves as a critical chiral building block and synthetic intermediate. Its rigid, functionalized structure makes it invaluable for constructing complex molecular architectures with precise three-dimensional control. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for applications in asymmetric synthesis, medicinal chemistry, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in neurological and metabolic disease research.
• Asymmetric Catalysis Ligand Precursor: Used to synthesize novel chiral ligands and organocatalysts for enantioselective transformations.
• Peptidomimetics & Constrained Peptide Design: Its bicyclic scaffold is incorporated to induce specific conformational restraints in peptide analogs, enhancing stability and biological activity.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and plant growth regulators with improved selectivity.
• Material Science Monomer: Potential use in creating specialty polymers with unique thermal or mechanical properties derived from its strained ring system.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic synthesis and for exploring new chemical space in drug discovery programs.

Basic Information

Product Name	Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, 2-Amino-3-Hydroxy-, (1R,2S,3R,4S)-Rel- (9Ci)
CAS No.	737748-06-0
Molecular Formula	C9H11NO3
Molecular Weight	181.19 g/mol
Synonyms	rel-(1R,2S,3R,4S)-2-Amino-3-hydroxybicyclo[2.2.1]hept-5-ene-2-carboxylic acid; 2-Amino-3-hydroxybicyclo[2.2.1]hept-5-ene-2-carboxylic acid (rel-(1R,2S,3R,4S)-); Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, 2-amino-3-hydroxy-, (1R,2S,3R,4S)-rel-; 737748-06-0; (1R,2S,3R,4S)-rel-2-Amino-3-hydroxybicyclo[2.2.1]hept-5-ene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, 2-Amino-3-Hydroxy-, (1R,2S,3R,4S)-Rel- (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure high chemical and stereochemical purity suitable for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.