Description

trans-2-(3-Fluorobenzoyl)Cyclohexane-1-Carboxylic Acid is a high-purity fluorinated organic building block of significant interest in advanced chemical synthesis. This compound matters as a versatile chiral intermediate, enabling the development of complex molecules with precise stereochemistry. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly where the introduction of a fluorinated aromatic moiety is required for bioactivity or metabolic stability.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the fluorine atom enhances lipophilicity and target binding.
• Ligand and Catalyst Development: Serves as a precursor for designing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and liquid crystals that require fluorinated aromatic components.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in chemical manufacturing.
• Academic & Contract Research: A valuable tool for synthetic organic chemistry research in universities and contract research organizations (CROs).

Basic Information

Product Name	trans-2-(3-Fluorobenzoyl)Cyclohexane-1-Carboxylic Acid
CAS No.	733742-79-5
Molecular Formula	C14H15FO3
Molecular Weight	250.27 g/mol
Synonyms	trans-2-(3-Fluorobenzoyl)cyclohexanecarboxylic acid; (1R,2R)-2-(3-Fluorobenzoyl)cyclohexane-1-carboxylic acid; (1S,2S)-2-(3-Fluorobenzoyl)cyclohexane-1-carboxylic acid; 2-[(3-Fluorophenyl)carbonyl]cyclohexanecarboxylic acid; 3-Fluoro-α-oxocyclohexanephenylacetic acid; 733742-79-5; trans-2-(3-Fluorobenzoyl)-1-cyclohexanecarboxylic Acid
EINECS	Contact for details

Quality Control

Our trans-2-(3-Fluorobenzoyl)Cyclohexane-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >97% by HPLC), enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.