Description

cis-3-(4-Fluorobenzoyl)Cyclopentane-1-Carboxylic Acid is a high-purity, functionalized cyclopentane derivative designed for advanced chemical synthesis. This compound serves as a critical chiral building block and intermediate in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by research and development teams, process chemists, and manufacturers within the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific stereochemistry and fluorinated aromatic motifs into complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and metabolic conditions.
• Agrochemical Research: Building block for developing new-generation herbicides, fungicides, and insecticides that leverage the fluorobenzoyl group for enhanced bioactivity and environmental stability.
• Ligand and Catalyst Development: Used in organometallic chemistry to create novel chiral ligands for asymmetric catalysis, improving the efficiency and selectivity of synthetic routes.
• Material Science: Intermediate for synthesizing specialized monomers or additives aimed at creating polymers with unique optical or thermal properties.
• Academic & Contract Research: Essential reagent for medicinal chemistry programs and process optimization studies in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	cis-3-(4-Fluorobenzoyl)Cyclopentane-1-Carboxylic Acid
CAS No.	732252-83-4
Molecular Formula	C13H13FO3
Molecular Weight	236.24 g/mol
Synonyms	3-[(4-Fluorophenyl)carbonyl]cyclopentane-1-carboxylic acid, cis- isomer; (1R,3S)-3-(4-Fluorobenzoyl)cyclopentane-1-carboxylic acid (for chiral form); (1S,3R)-3-(4-Fluorobenzoyl)cyclopentane-1-carboxylic acid; 4-Fluoro-α-oxocyclopentanepropanoic acid; 3-(p-Fluorobenzoyl)cyclopentanecarboxylic acid; FCB-CPA; Fluorobenzoyl cyclopentane carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of cis-3-(4-Fluorobenzoyl)Cyclopentane-1-Carboxylic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure compliance with exacting customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity (where applicable), and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (for chiral-specific grade)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.