Description

cis-3-(3-Fluorobenzoyl)Cyclopentane-1-Carboxylic Acid is a high-purity fluorinated carboxylic acid derivative, serving as a critical advanced pharmaceutical intermediate (API) and versatile building block in organic synthesis. Its value lies in the precise structural combination of a cyclopentane carboxylic acid core and a meta-fluorinated benzoyl group, enabling targeted modifications in complex molecule development. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate a specific fluorinated moiety into novel active compounds.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel Active Pharmaceutical Ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, metabolic diseases, and inflammation.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity, stability, and metabolic profile.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and transition metal catalysis.
• Material Science Research: Employed in the synthesis of monomers and polymers for advanced materials, where the fluorinated aromatic group can influence thermal stability and solubility.
• Fluorine Chemistry Studies: A valuable substrate for investigating structure-activity relationships (SAR) and the effects of fluorine substitution in medicinal and synthetic chemistry.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and contract research organizations (CROs/CMOs) producing bespoke fluorinated compounds for clients.

Basic Information

Product Name	cis-3-(3-Fluorobenzoyl)Cyclopentane-1-Carboxylic Acid
CAS No.	732252-75-4
Molecular Formula	C13H13FO3
Molecular Weight	236.24 g/mol
Synonyms	3-(3-Fluorobenzoyl)cyclopentane-1-carboxylic acid (cis-); cis-3-(3-Fluorobenzoyl)cyclopentanecarboxylic acid; (1R,3S)-3-(3-Fluorobenzoyl)cyclopentane-1-carboxylic acid (enantiomer); (1S,3R)-3-(3-Fluorobenzoyl)cyclopentane-1-carboxylic acid (enantiomer); 3-(3-Fluorobenzoyl)cyclopentanecarboxylic Acid; Fluorobenzoyl Cyclopentanecarboxylic Acid Derivative; 732252-75-4; FCBA Intermediate
EINECS	Contact for details

Quality Control

Our cis-3-(3-Fluorobenzoyl)Cyclopentane-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our production adheres to cGMP principles where applicable, ensuring reliable supply for critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.