Description

Ethyl 4-Fluoro-3-Methylbenzoylformate is a high-purity fluorinated aromatic ester building block of significant interest in advanced organic synthesis. Its core value lies in its versatile molecular scaffold, which is designed for the efficient construction of complex pharmacophores and agrochemical intermediates. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal Material Research: Serves as a building block for fluorinated mesogens in the development of advanced display technologies.
• Organic Light-Emitting Diode (OLED) Materials: Employed in the synthesis of electron-transport or host materials for efficient OLED devices.
• Chemical Research & Development: A versatile reagent for method development in cross-coupling reactions and carbonyl chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client pipelines.

Basic Information

Product Name	Ethyl 4-Fluoro-3-Methylbenzoylformate
CAS No.	732251-71-7
Molecular Formula	C11H11FO3
Molecular Weight	210.20 g/mol
Synonyms	Ethyl 2-(4-Fluoro-3-methylphenyl)-2-oxoacetate; 2-Oxo-2-(4-fluoro-3-methylphenyl)acetic Acid Ethyl Ester; 4-Fluoro-3-methylbenzoylformic Acid Ethyl Ester; Ethyl (4-Fluoro-3-methylbenzoyl)formate; Ethyl α-Oxo-4-fluoro-3-methylbenzeneacetate; Ethyl 4-Fluoro-3-methyl-α-oxobenzeneacetate
EINECS	Contact for details

Quality Control

Our Ethyl 4-Fluoro-3-Methylbenzoylformate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and scale-up applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.