Description

Ethyl 3-Fluoro-4-Methylbenzoylformate is a high-purity fluorinated aromatic ester building block of significant interest in advanced organic synthesis. Its core value lies in its versatile molecular scaffold, which serves as a critical precursor for the development of complex, biologically active molecules. This compound is primarily needed by research and development teams within the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of advanced organic materials, such as liquid crystals or organic semiconductors, where fluorination tunes electronic properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific fluorinated aromatic intermediates.

Basic Information

Product Name	Ethyl 3-Fluoro-4-Methylbenzoylformate
CAS No.	732251-65-9
Molecular Formula	C11H11FO3
Molecular Weight	210.20 g/mol
Synonyms	Ethyl 3-Fluoro-4-methyl-2-oxo-2-phenylacetate; Ethyl (3-Fluoro-4-methylphenyl)(oxo)acetate; 3-Fluoro-4-methylbenzoylformic Acid Ethyl Ester; 2-Oxo-2-(3-fluoro-4-methylphenyl)acetic Acid Ethyl Ester; Ethyl α-oxo-3-fluoro-4-methylbenzeneacetate; Ethyl 2-(3-Fluoro-4-methylphenyl)-2-oxoacetate; Phenylglyoxylic acid, 3-fluoro-4-methyl-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 3-Fluoro-4-Methylbenzoylformate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed batch-specific data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.