Description

Atripla CAS NO 731772-50-2 is a fixed-dose combination antiretroviral medication. It is a critical therapeutic agent in the global management of Human Immunodeficiency Virus (HIV-1) infection, offering a simplified treatment regimen. This product is essential for pharmaceutical manufacturers, research institutions, and public health organizations involved in HIV therapy and drug development.

Application

• HIV-1 Treatment: Primary use as a complete, once-daily oral regimen for the treatment of HIV-1 infection in adults and pediatric patients.
• Pharmaceutical Manufacturing: Serves as the active pharmaceutical ingredient (API) for the formulation of generic and branded antiretroviral tablets.
• Clinical Research: Used in comparative studies, bioequivalence testing, and the development of new therapeutic protocols and combination therapies.
• Public Health Programs: Supplied for use in national and international HIV/AIDS treatment and prevention initiatives.
• Drug Development: Utilized as a reference standard in analytical laboratories for quality control and method validation.

Basic Information

Product Name	Atripla
CAS No.	731772-50-2
Molecular Formula	C23H23F3N3O5S • C14H18N6O • C8H10FN3O3S
Molecular Weight	Contact for details
Synonyms	Efavirenz/Emtricitabine/Tenofovir Disoproxil Fumarate; EFV/FTC/TDF; Atripla Tablets; BMS-986001/GS-7340/GS-1278 (component-related); Sustiva + Truvada (combination); TLE (Tenofovir Lamivudine Efavirenz) alternative; Fixed-Dose Combination Antiretroviral; HIV Triple Therapy Drug.
EINECS	Contact for details

Quality Control

Our Atripla is manufactured and tested to meet stringent pharmaceutical standards. Quality assurance protocols align with current Good Manufacturing Practices (cGMP) and relevant pharmacopoeial guidelines (e.g., USP, EP). Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, potency, and impurity profiles to ensure reliability and consistency for formulation and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Description	White to off-white powder or solid mixture
Identification (HPLC)	Conforms to reference standards
Assay (HPLC)	90.0% - 110.0% of labeled claim for each component
Related Substances (HPLC)	Individual impurity: NMT 0.5% Total impurities: NMT 2.0%
Water Content (KF)	NMT 5.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	NMT 20 ppm
Microbial Limits	Complies with Ph. Eur. / USP <61>, <62>

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.