Description

(1S,2R)-2-Aminocyclobutan-1-Ol CAS NO 724419-25-4 is a high-purity, chiral aminocyclobutanol derivative, a valuable building block in modern organic synthesis. This compound matters as a key chiral intermediate for the development of novel pharmaceuticals and agrochemicals, enabling the creation of stereochemically defined molecules with enhanced biological activity. It is primarily needed by research and development chemists, process development teams, and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Research: Used in the development of novel, stereoselective herbicides, fungicides, and insecticides where specific chirality impacts efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Peptidomimetics and Bioactive Molecules: Incorporated into the backbone of peptidomimetics and other bioactive compounds to modulate conformation, stability, and receptor binding.
• Academic and Industrial R&D: A valuable tool for methodological development in organic chemistry and for exploring new chemical space in drug discovery programs.
• Custom Synthesis and Contract Manufacturing: Supplied for custom synthesis projects requiring high-fidelity chiral building blocks under cGMP or non-GMP conditions.

Basic Information

Product Name	(1S,2R)-2-Aminocyclobutan-1-Ol
CAS No.	724419-25-4
Molecular Formula	C4H9NO
Molecular Weight	87.12 g/mol
Synonyms	(1S,2R)-2-Aminocyclobutanol; (1S,2R)-2-Amino-1-cyclobutanol; (1S,2R)-1-Cyclobutanol-2-amine; (1S,2R)-2-Aminocyclobutan-1-ol; trans-2-Aminocyclobutanol; (1S,2R)-Aminocyclobutanol; 2-Aminocyclobutan-1-ol (1S,2R)-form
EINECS	Contact for details

Quality Control

Our (1S,2R)-2-Aminocyclobutan-1-Ol is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chiral purity. We provide comprehensive analytical data, including chiral HPLC for enantiomeric excess (ee) determination. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch. Our quality system supports development from research to commercial scale, with documentation tailored to meet cGMP and other relevant regulatory standards as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent absorption of atmospheric moisture, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.