Description

3-((4-Fluorobenzyl)Amino)Benzoic Acid is a high-purity organic intermediate featuring a benzoic acid core substituted with a (4-fluorobenzyl)amino group. This compound matters for its role as a versatile building block in the synthesis of more complex molecules, particularly in pharmaceutical research and development. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors seeking to introduce specific fluorinated aromatic motifs into their target compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders or requiring fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides where the fluorine atom and the aniline-benzoic acid structure can contribute to biological activity and environmental persistence profiles.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands used in asymmetric catalysis or metal-organic frameworks (MOFs), leveraging the coordinating ability of the carboxylic acid and amino groups.
• Fluorescent Probe and Dye Chemistry: Acts as a starting material for synthesizing fluorophore derivatives and functional dyes used in bio-imaging, sensors, and analytical chemistry applications.
• Polymer Modification: Employed to introduce functional aromatic amines and carboxylic acids into polymer backbones, modifying properties like thermal stability, solubility, and reactivity for advanced material science.
• Academic and Contract Research: Essential for medicinal chemistry programs in universities and CROs (Contract Research Organizations) exploring structure-activity relationships (SAR) in drug discovery projects.

Basic Information

Product Name	3-((4-Fluorobenzyl)Amino)Benzoic Acid
CAS No.	718602-89-2
Molecular Formula	C14H12FNO2
Molecular Weight	245.25 g/mol
Synonyms	3-[(4-Fluorophenyl)methylamino]benzoic acid; Benzoic acid, 3-[[(4-fluorophenyl)methyl]amino]-; 3-((4-Fluorobenzyl)amino)benzoic acid; 3-[(4-Fluorobenzyl)amino]benzoic acid; N-(4-Fluorobenzyl)anthranilic acid; 3-Amino-N-(4-fluorobenzyl)benzoic acid; 718602-89-2; 3-(4-Fluorobenzylamino)benzoic acid
EINECS	Contact for details

Quality Control

Our 3-((4-Fluorobenzyl)Amino)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (HPLC), related substances, and residual solvents. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.