Description

Vidofludimus is a high-purity, small molecule pharmaceutical intermediate and research chemical. This compound is of significant interest for its role as a selective inhibitor of dihydroorotate dehydrogenase (DHODH), a key enzyme in the *de novo* pyrimidine synthesis pathway. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of novel immunomodulatory and anti-inflammatory therapeutics. Vidofludimus CAS NO 717824-30-1 represents a critical building block for advanced medical research.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting autoimmune diseases.
• Immunology Research: Used as a potent and selective DHODH inhibitor in *in vitro* and *in vivo* studies to investigate immune cell function and proliferation.
• Inflammatory Disease R&D: A vital tool compound for developing novel treatments for conditions like multiple sclerosis, rheumatoid arthritis, and lupus.
• Biochemical Assay Development: Employed as a standard or reference compound in high-throughput screening (HTS) and enzymatic assays.
• Preclinical Studies: Utilized in animal model research to evaluate pharmacokinetics, efficacy, and safety profiles of new drug candidates.
• Process Chemistry: Acts as a starting material or intermediate for scale-up synthesis under current Good Manufacturing Practice (cGMP) conditions.

Basic Information

Product Name	Vidofludimus
CAS No.	717824-30-1
Molecular Formula	C₁₆H₁₃F₂N₃O₃
Molecular Weight	333.29 g/mol
Synonyms	4SC-101; (S)-2-((3-Fluoro-4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)carbamoyl)-5-methyl-4,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidine-4-carboxylic acid; SC12267; DHODH Inhibitor Vidofludimus; 4SC101; BAY 1187982
EINECS	Contact for details

Quality Control

Our Vidofludimus is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and impurities. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.