Description

2-Fluoro-5-Methylsulfamoyl-Benzoic Acid is a high-purity, functionalized benzoic acid derivative designed for advanced chemical synthesis. This compound serves as a critical building block in pharmaceutical research and development, offering a unique combination of fluorine and sulfonamide pharmacophores. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific bioactivity and physicochemical properties into new molecular entities.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in sulfonamide-based drug candidates.
• Agrochemical Research: Used in the synthesis of advanced herbicides and fungicides, leveraging the fluorine atom for enhanced metabolic stability and bioavailability.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme inhibition and receptor binding mechanisms.
• Material Science: Acts as a monomer or functionalizing agent for creating specialty polymers with tailored surface properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific, multi-step synthetic routes.

Basic Information

Product Name	2-Fluoro-5-Methylsulfamoyl-Benzoic Acid
CAS No.	716358-53-1
Molecular Formula	C8H8FNO4S
Molecular Weight	233.22 g/mol
Synonyms	5-(Methylsulfamoyl)-2-fluorobenzoic acid; 2-Fluoro-5-(N-methylsulfamoyl)benzoic acid; Benzoic acid, 2-fluoro-5-[(methylamino)sulfonyl]-; 2-Fluoro-5-methylaminosulfonylbenzoic acid; 716358-53-1; 2-Fluoro-5-(methylsulfamoyl)benzoic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-5-Methylsulfamoyl-Benzoic Acid is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard grade meets high-purity requirements suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.