Description

Ccr5 Antagonist 1 CAS NO 716354-86-8 is a high-purity, small molecule chemical compound designed for advanced pharmaceutical research and development. This compound serves as a potent and selective antagonist of the CCR5 chemokine receptor, a critical target in immunology and virology. It is primarily utilized by research scientists and process chemists in the pharmaceutical and biotechnology industries for drug discovery programs, particularly in the fields of HIV therapeutics, inflammatory diseases, and oncology.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in API manufacturing.
• Drug Discovery & Preclinical Research: Serves as a key pharmacologically active compound for in vitro and in vivo studies targeting the CCR5 receptor pathway.
• Biochemical Assay Development: Employed in high-throughput screening (HTS) and binding assays to evaluate new drug candidates and study receptor-ligand interactions.
• Process Chemistry & Impurity Synthesis: Used as an intermediate or a synthetic precursor in the development and scale-up of novel therapeutic agents.
• Academic & Institutional Research: A vital tool for universities and research institutes studying immunology, virology (specifically HIV-1 entry inhibition), and cell signaling mechanisms.

Basic Information

Product Name	Ccr5 Antagonist 1
CAS No.	716354-86-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	CCR5 Antagonist 1; CCR5 Receptor Antagonist 1; 716354-86-8; (Compound) TAK-220; TAK 220; TAK220; Maraviroc analogue; HIV entry inhibitor; Chemokine receptor antagonist
EINECS	Contact for details

Quality Control

Every batch of Ccr5 Antagonist 1 is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to protect the compound from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.