Description

Cyclohexanecarboxylic Acid, 1-Fluoro-4-Methyl- (9Ci) is a fluorinated cyclohexane derivative that serves as a versatile and valuable building block in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid and a fluorine substituent on the cyclohexane ring, makes it a critical intermediate for introducing specific steric and electronic properties into target molecules. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of fluorinated drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-inflammatory agents, and metabolic disease treatments.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity, stability, and metabolic resistance.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in advanced electronic display materials, contributing to improved dielectric anisotropy and thermal stability.
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with enhanced chemical resistance, lower surface energy, or specific optical properties.
• Catalyst & Ligand Development: Utilized in the synthesis of novel chiral ligands and organocatalysts for asymmetric synthesis, leveraging the steric influence of the cyclohexyl backbone.
• Chemical Research & Development: Employed in academic and industrial R&D labs as a standard or probe molecule for studying fluorination effects and reaction mechanisms.

Basic Information

Product Name	Cyclohexanecarboxylic Acid, 1-Fluoro-4-Methyl- (9Ci)
CAS No.	712353-87-2
Molecular Formula	C8H13FO2
Molecular Weight	160.18 g/mol
Synonyms	1-Fluoro-4-methylcyclohexanecarboxylic acid; 4-Methyl-1-fluorocyclohexanecarboxylic acid; (1-Fluoro-4-methylcyclohexyl)formic acid; Fluoromethylcyclohexanecarboxylic acid; trans/cis-1-Fluoro-4-methylcyclohexanecarboxylic acid (mixture); Cyclohexanecarboxylic acid, 1-fluoro-4-methyl-; 712353-87-2
EINECS	Contact for details

Quality Control

Every batch of Cyclohexanecarboxylic Acid, 1-Fluoro-4-Methyl- (9Ci) is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as assay purity (typically by HPLC or GC) and impurity profiles. Our quality commitment supports compliance with cGMP guidelines where applicable for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound may be sensitive to strong bases and fluorophilic reagents; keep away from incompatible materials. For long-term storage, consider using an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥97.0% (typical 98.0-99.5%)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤2.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.