Description

Letermovir is a potent antiviral agent specifically designed to target and inhibit the cytomegalovirus (CMV) terminase complex. This compound is of critical importance for the prevention and treatment of CMV infections, particularly in immunocompromised patient populations such as transplant recipients. It is essential for pharmaceutical manufacturers, research institutions, and contract development and manufacturing organizations (CDMOs) engaged in antiviral drug development and production.

Application

• Active Pharmaceutical Ingredient (API) for the formulation of antiviral medications targeting cytomegalovirus (CMV).
• Research and Development of novel antiviral therapies and combination treatments.
• Reference Standard for analytical method development and quality control in pharmaceutical laboratories.
• Clinical Trial Material for studies investigating new indications or formulations of letermovir.
• Process Development for the optimization of synthetic routes and scale-up manufacturing.
• Biochemical Research to study the mechanism of action of viral terminase inhibitors.

Basic Information

Product Name	Letermovir
CAS No.	710312-77-9
Molecular Formula	C₂₉H₂₈F₄N₄O₄
Molecular Weight	572.55 g/mol
Synonyms	Letermovir; AIC246; MK-8228; 4-Fluoro-2-hydroxy-5-methoxy-N-[1-methyl-2-(4-{[5-methyl-6-(methylcarbamoyl)-2-pyridinyl]ethynyl}phenyl)ethyl]benzamide; Prevymis (Brand Name)
EINECS	Contact for details

Quality Control

Our Letermovir is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and can be tailored to meet specific pharmacopeial or client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature, 15-25°C (59-77°F). The product is hygroscopic (moisture-sensitive) and should be kept in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5% Any single unknown impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.