Description

Belatacept is a selective T-cell costimulation blocker, a fusion protein used as an immunosuppressive agent. It is a critical therapeutic for preventing organ transplant rejection by modulating the immune response. This product is essential for pharmaceutical manufacturers and research institutions developing advanced immunosuppressive therapies.

Application

• Primary active pharmaceutical ingredient (API) in immunosuppressive medications.
• Key component in the formulation of injection solutions for prophylaxis of organ rejection in adult patients receiving a kidney transplant.
• Used in clinical research for studying T-cell activation and costimulation pathways.
• Reference standard in analytical laboratories for quality control and method development.
• Investigational material for developing novel biologic drug conjugates or delivery systems.

Basic Information

Product Name	Belatacept
CAS No.	706808-37-9
Molecular Formula	C3398H5308N922O1018S44
Molecular Weight	~90 kDa
Synonyms	BMS-224818; LEA29Y; Nulojix; CTLA4-Ig; Abatacept variant LEA29Y; Recombinant fusion protein CTLA4-Ig (LEA29Y); Selective T-cell costimulation blocker; Belataceptum
EINECS	Contact for details

Quality Control

Our Belatacept is manufactured under strict quality systems. Each batch is subjected to a comprehensive suite of analytical tests including identity, purity, potency, and impurity profiling to ensure it meets stringent pharmaceutical-grade standards. Certificates of Analysis (COA) detailing specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive) and must be kept under controlled humidity conditions. For long-term storage, consider maintaining the product in its original sealed packaging under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (SEC-HPLC)	≥ 98.0% (Monomer)
Assay (Bioassay)	90% - 110% of labeled potency
Protein Content	As per COA
Endotoxin	< 1.0 EU/mg
Residual Moisture (KF)	< 3.0%
Sterility	Sterile (where applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.