Description

Sertraline CAS NO 79617-96-2 is a high-purity active pharmaceutical ingredient (API) belonging to the selective serotonin reuptake inhibitor (SSRI) class. It is a critical compound for the development and manufacturing of effective antidepressant and anti-anxiety medications. This product is essential for pharmaceutical companies, research institutions, and contract manufacturing organizations (CMOs) engaged in the production of finished dosage forms and advanced therapeutic research.

Application

• Pharmaceutical API: Primary active ingredient in the manufacture of antidepressant tablets, capsules, and oral solutions.
• Generic Drug Formulation: Key component for developing bioequivalent generic versions of sertraline hydrochloride medications.
• Clinical Research Materials: Used as a reference standard or raw material in preclinical and clinical studies for central nervous system disorders.
• Contract Manufacturing: Supplied to CMOs for the production of finished pharmaceutical products under GMP guidelines.
• Analytical Standard: Serves as a high-purity standard for quality control testing, method development, and validation in analytical laboratories.

Basic Information

Product Name	Sertraline
CAS No.	79617-96-2
Molecular Formula	C17H17Cl2N
Molecular Weight	306.23 g/mol
Synonyms	(1S,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine; (1S-cis)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine; CP-51974-01; Zoloft (API); Lustral (API); Sertraline Base
EINECS	Contact for details

Quality Control

Our Sertraline is manufactured and tested under strict quality management systems. We ensure compliance with major pharmacopoeial standards, including USP and EP monographs. Every batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles to meet the stringent requirements of pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 1.0%
Individual Unknown Impurity	≤ 0.10%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 0.5%
Sulfated Ash	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.