Description

Hydroxyethylclavam CAS NO 79416-52-7 is a semi-synthetic β-lactamase inhibitor derived from the clavulanic acid family. This compound is valued for its synergistic role in enhancing the efficacy of β-lactam antibiotics against resistant bacterial strains. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development of advanced antibacterial formulations and combination therapies.

Application

• Pharmaceutical Intermediates: Key building block in the synthesis of next-generation β-lactamase inhibitor combinations.
• Antibiotic Potentiation: Used in research and production to restore the activity of penicillins and cephalosporins against β-lactamase-producing bacteria.
• Veterinary Medicine: Incorporated into animal health products to combat bacterial infections and address antimicrobial resistance.
• Clinical Research: Serves as a critical reference standard and active material in microbiological and pharmacokinetic studies.
• API Synthesis: Intermediate in the manufacturing process of active pharmaceutical ingredients (APIs) for combination antibacterial drugs.

Basic Information

Product Name	Hydroxyethylclavam
CAS No.	79416-52-7
Molecular Formula	C9H13NO5
Molecular Weight	215.20 g/mol
Synonyms	(2R,3Z,5R)-3-(2-Hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid; Hydroxyethylclavulanate; BRL 36650; (Z)-2-(2-Hydroxyethylidene)clavam-2-carboxylic Acid; Clavulanic Acid Hydroxyethyl Derivative
EINECS	Contact for details

Quality Control

Our Hydroxyethylclavam is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling via HPLC and spectroscopic methods, to ensure it meets exacting standards for pharmaceutical research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.