Description

(S)-(+)-3-Hydroxytetrahydrofuran is a high-value chiral building block and versatile intermediate in organic synthesis. Its enantiopure nature is critical for the production of optically active pharmaceuticals and fine chemicals, ensuring the desired biological activity and regulatory compliance. This compound is essential for research and manufacturing in the pharmaceutical, agrochemical, and specialty chemical industries, where precise stereochemistry is paramount.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, cardiovascular, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Building block for fragrances, flavors, and other high-value specialty chemicals requiring specific stereochemistry.
• Polymer Chemistry: Monomer for creating functionalized polymers with tailored properties.
• Academic & Industrial R&D: Valuable reagent for methodological development in organic chemistry and process optimization.

Basic Information

Product Name	(S)-(+)-3-Hydroxytetrahydrofuran
CAS No.	79107-75-8
Molecular Formula	C4H8O2
Molecular Weight	88.11 g/mol
Synonyms	(S)-3-Hydroxytetrahydrofuran; (S)-(+)-Tetrahydro-3-furanol; (3S)-Oxolan-3-ol; (S)-Tetrahydro-3-furanol; (S)-3-Hydroxyoxolane; (S)-3-THF-OH; (S)-3-Hydroxytetrahydrofuran; (S)-3-THFOL
EINECS	Contact for details

Quality Control

Our (S)-(+)-3-Hydroxytetrahydrofuran is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity determination by HPLC and GC, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to support regulatory filings (e.g., FDA, EMA).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation [α]	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.