Description

Meta Fluoxetine Hydrochloride CAS NO 79088-29-2 is the hydrochloride salt of a key intermediate in the synthesis of the widely used antidepressant, Fluoxetine. This high-purity intermediate is critical for ensuring the final Active Pharmaceutical Ingredient (API) meets stringent pharmacopeial standards for identity, purity, and potency. It is an essential building block for pharmaceutical manufacturers and R&D facilities engaged in the production and development of selective serotonin reuptake inhibitor (SSRI) medications.

Application

• Pharmaceutical Synthesis: Primary use as a critical intermediate in the commercial-scale manufacturing of Fluoxetine Hydrochloride API.
• Generic Drug Production: Sourcing for manufacturers producing generic versions of antidepressant formulations containing Fluoxetine.
• Research & Development: Utilized in pharmaceutical R&D for developing new dosage forms, controlled-release mechanisms, or novel SSRI derivatives.
• Process Chemistry & Optimization: Serves as a reference standard or starting material for scaling up and optimizing synthetic routes in process chemistry.
• Analytical Reference Standard: Can be used to develop and validate analytical methods (e.g., HPLC, GC) for quality control of the final API.

Basic Information

Product Name	Meta Fluoxetine Hydrochloride
CAS No.	79088-29-2
Molecular Formula	C17H19F3NO • HCl
Molecular Weight	345.79 g/mol (Free base: 309.33)
Synonyms	N-Methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propylamine hydrochloride; 3-(p-Trifluoromethylphenoxy)-3-phenyl-N-methylpropylamine HCl; Fluoxetine Intermediate HCl; (±)-N-Methyl-γ-[4-(trifluoromethyl)phenoxy]benzenepropanamine hydrochloride; LY110140 intermediate
EINECS	Contact for details

Quality Control

Our Meta Fluoxetine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical synthesis. We provide detailed Certificates of Analysis (COA) that include data for identity, assay, purity, and specified impurities, supporting compliance with cGMP and ICH guidelines. Specifications can be aligned with customer-specific or pharmacopeial requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.