Description

2'-Fluoro-5-Methylarabino-Furanosylcytosine is a fluorinated nucleoside analog, a key building block in advanced pharmaceutical research and development. This compound is valued for its role as a synthetic intermediate in the creation of novel antiviral and anticancer therapeutics. It is primarily utilized by research institutions, pharmaceutical companies, and CDMOs engaged in the synthesis of modified nucleosides and oligonucleotides for targeted drug discovery programs.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel antiviral and anticancer nucleoside analogs.
• Antiviral Drug Research: Used in the development of potential therapeutics targeting viral polymerases and replication mechanisms.
• Oncology Research: Serves as a precursor in the design of chemotherapeutic agents that interfere with DNA/RNA synthesis in cancer cells.
• Oligonucleotide Synthesis: Employed in the production of modified oligonucleotides for antisense, siRNA, and aptamer technologies.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to understand cellular processes.
• Process Development & Scale-up: Sourced by contract manufacturing organizations (CMOs) for process optimization and commercial-scale API production.

Basic Information

Product Name	2'-Fluoro-5-Methylarabino-Furanosylcytosine
CAS No.	78636-53-0
Molecular Formula	C10H12FN3O5
Molecular Weight	273.22 g/mol
Synonyms	2'-Fluoro-5-methylcytosine arabinoside; 1-(2-Deoxy-2-fluoro-5-methyl-β-D-arabinofuranosyl)cytosine; 2'-F-5-Me-ara-C; 5-Methyl-2'-fluoro-ara-cytidine; 2'-Fluoro-5-methyl-1-β-D-arabinofuranosylcytosine; 5-Methyl-2'-fluoro-arabinofuranosyl cytosine; 2'-F-5-MethylaraC
EINECS	Contact for details

Quality Control

Our 2'-Fluoro-5-Methylarabino-Furanosylcytosine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to current industry standards, and specifications can be aligned with client requirements for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.