Description

n-(Estradiol-17 β-Succinylaminohexyl)-N'-Fluoresceinyl-Thiourea CAS NO 78232-36-7 is a high-purity, fluorescent-labeled steroid derivative designed for advanced research and diagnostic applications. This compound is critical for scientists requiring highly specific and sensitive detection methods in biochemical assays. It is primarily utilized by researchers and developers in the fields of endocrinology, molecular biology, and pharmaceutical development for applications such as receptor binding studies, immunoassays, and fluorescence microscopy.

Application

• Fluorescent Labeling in Receptor Binding Assays: Used to study the binding affinity and kinetics of estrogen receptors with high sensitivity.
• Development of Diagnostic Kits: Serves as a key tracer or conjugate in immunoassays and other in vitro diagnostic (IVD) platforms for hormone detection.
• Cellular Imaging and Microscopy: Enables visualization and tracking of steroid hormone pathways and interactions within live or fixed cells.
• Biochemical Research Probes: Acts as a specialized tool compound for investigating steroid hormone action, signal transduction, and related metabolic pathways.
• Pharmaceutical R&D: Employed in high-throughput screening (HTS) and drug discovery programs targeting hormone-related diseases.

Basic Information

Product Name	n-(Estradiol-17 β-Succinylaminohexyl)-N'-Fluoresceinyl-Thiourea
CAS No.	78232-36-7
Molecular Formula	C49H55N3O9S
Molecular Weight	862.05 g/mol
Synonyms	Estradiol-Fluorescein Conjugate; Estradiol-17β-Succinyl-6-Aminohexyl-Fluorescein Thiourea; 17β-Estradiol-6-CMO-Fluorescein; Fluorescein-labeled Estradiol; FE1; Fluorescent Estrogen Derivative; E2-FITC Conjugate; 6-[(17β-3-Hydroxyestra-1,3,5(10)-trien-17-yl)succinylamino]hexyl-3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-carbothioamide
EINECS	Contact for details

Quality Control

Our n-(Estradiol-17 β-Succinylaminohexyl)-N'-Fluoresceinyl-Thiourea is manufactured under strict quality management systems to ensure batch-to-batch consistency and high performance in sensitive applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and fluorescence spectroscopy. A detailed Certificate of Analysis (COA) documenting identity, purity, and specific performance characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider under an inert atmosphere. Allow the product to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Orange to red solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Extinction Coefficient	Contact for details
Fluorescence Properties	Contact for details
Solubility	Soluble in DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.