Description

Benzoyl Fluoride, 4-Acetyl- (9Ci) CAS NO 77976-03-5 is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its unique reactivity profile, where the benzoyl fluoride moiety serves as a versatile acylating agent, and the acetyl group provides a handle for further functionalization. It is primarily needed by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, particularly in the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially those requiring fluorinated aromatic cores for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the fluorine atom can improve biological activity and environmental persistence.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials with tailored properties.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for catalysis or as a precursor for metal-organic frameworks (MOFs) in catalytic applications.
• Fluorination Chemistry Research: A valuable substrate for studying new fluorination methodologies and the behavior of acyl fluoride groups in complex reaction environments.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex fragrance, flavor, and dye molecules requiring specific fluorinated ketone structures.

Basic Information

Product Name	Benzoyl Fluoride, 4-Acetyl- (9Ci)
CAS No.	77976-03-5
Molecular Formula	C9H7FO2
Molecular Weight	166.15 g/mol
Synonyms	4-Acetylbenzoyl Fluoride; 1-[4-(Fluorocarbonyl)phenyl]ethanone; p-Acetylbenzoyl Fluoride; 4-Acetylbenzoyl Fluoride (9CI); 4-Acetyl-benzoyl fluoride; Ethanone, 1-[4-(fluorocarbonyl)phenyl]-; 4-Acetylbenzoyl fluoride; 4'-Acetylbenzoyl fluoride
EINECS	Contact for details

Quality Control

Our Benzoyl Fluoride, 4-Acetyl- (9Ci) is produced under stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. While typically supplied in laboratory or development quantities, each lot undergoes rigorous analytical testing. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical range 95-98%)
Melting Point	Contact for details
Water Content (KF)	< 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.