Description

4-Amino-2-Methoxybenzoic Acid [Carboxyl-14C] is a carbon-14 labeled derivative of 4-amino-2-methoxybenzoic acid, a key intermediate in organic synthesis. This radiolabeled compound is essential for conducting precise metabolic, pharmacokinetic, and environmental fate studies, providing critical data on molecular pathways and degradation. It is primarily required by research scientists and process chemists in the pharmaceutical, agrochemical, and life science industries for advanced tracer applications and analytical method development.

Application

• Tracer Studies in Drug Metabolism and Pharmacokinetics (DMPK): Used to track the absorption, distribution, metabolism, and excretion (ADME) of new chemical entities in preclinical research.
• Environmental Fate and Degradation Analysis: Employed in agrochemical research to study the breakdown pathways and persistence of active ingredients in soil and water systems.
• Biochemical Pathway Elucidation: Serves as a labeled precursor or intermediate for investigating specific biosynthetic or catabolic routes in biological systems.
• Analytical Method Development and Validation: Acts as an internal standard or reference material in Liquid Chromatography-Mass Spectrometry (LC-MS) and other chromatographic assays.
• Radiochemical Synthesis: Functions as a building block for the preparation of more complex carbon-14 labeled target molecules for research purposes.
• Quality Control and Impurity Profiling: Used in pharmaceutical development to identify, quantify, and track potential genotoxic impurities or degradation products.

Basic Information

Product Name	4-Amino-2-Methoxybenzoic Acid [Carboxyl-14C]
CAS No.	77891-87-3
Molecular Formula	C8H9NO3 (with 14C label at the carboxyl carbon)
Molecular Weight	~167.16 g/mol (unlabeled)
Synonyms	2-Methoxy-4-aminobenzoic Acid-14C; 4-Amino-o-anisic Acid-14C; 4-Amino-2-methoxy-[carboxy-14C]benzoic Acid; 2-Methoxy-4-aminobenzoic Acid (Carboxyl-14C); [Carboxyl-14C]-4-Amino-2-methoxybenzoic Acid; 4-Amino-2-methoxybenzoic-14C acid; 4-Amino-2-methoxy[14C]benzoic Acid
EINECS	Contact for details

Quality Control

Every batch of our 4-Amino-2-Methoxybenzoic Acid [Carboxyl-14C] is produced and analyzed under strict quality systems to ensure traceability and reliability for critical research. We provide comprehensive Certificates of Analysis (COA) detailing radiochemical purity, specific activity, chemical purity, and isotopic enrichment. Our quality commitment aligns with the stringent requirements for radiolabeled compounds used in GLP (Good Laboratory Practice) and regulatory submission studies.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. This material is light-sensitive (store away from light). For long-term stability, store the sealed vial in an appropriate shielded container in a dedicated, well-ventilated area for radioactive materials, following all local and institutional radiation safety protocols.

Specification

Item	Specification
Appearance	White to Off-White Solid
Identification (IR)	Conforms to Structure
Assay (HPLC)	≥ 98% (Chemical Purity)
Radiochemical Purity (Radio-HPLC)	≥ 97%
Specific Activity	50-60 mCi/mmol (Contact for specific value)
Solubility	Soluble in DMSO, Methanol; Slightly soluble in Water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.