Description

[R,(-)]-4-Dimethylamino-α,2-Dimethylphenethylamine is a chiral amine compound of significant interest in advanced organic synthesis. This product matters as a high-purity, stereochemically defined building block, enabling the development of complex molecules with precise biological activity. It is primarily needed by research and development teams in the pharmaceutical and fine chemical industries for applications such as chiral ligand synthesis and as a key intermediate in medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting neurological and cardiovascular pathways.
• Chiral Ligand/ Catalyst Precursor: Used in the development of asymmetric catalysts for enantioselective synthesis, improving yield and purity of desired stereoisomers.
• Medicinal Chemistry Research: Serves as a core scaffold in drug discovery for structure-activity relationship (SAR) studies and lead optimization.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals and agrochemicals.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	[R,(-)]-4-Dimethylamino-α,2-Dimethylphenethylamine
CAS No.	77518-08-2
Molecular Formula	C12H20N2
Molecular Weight	192.30 g/mol
Synonyms	(R)-(-)-4-(Dimethylamino)-α,2-dimethylphenethylamine; (R)-2-[4-(Dimethylamino)-2-methylphenyl]-1-methylethylamine; (1R)-1-(4-Dimethylamino-2-methylphenyl)propan-2-amine; (R)-4-Dimethylamino-α,2-dimethylphenethylamine; (-)-4-Dimethylamino-α,2-dimethylphenethylamine; R-(-)-DMADMPA; (R)-DMADMPA
EINECS	Contact for details

Quality Control

Our [R,(-)]-4-Dimethylamino-α,2-Dimethylphenethylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.