Description

(+)-(10,11-Dihydro-5-Methyl-5H-Dibenzo[A,D]Cyclohepten-5,10-Diyl)Ammonium Hydrogen [S-(R*,R*)]-2,3-Bis(p-Toluoyloxy)Succinate is a high-purity, chiral organic salt of significant interest in advanced pharmaceutical synthesis. This compound matters as a critical intermediate or resolving agent for the production of enantiomerically pure active pharmaceutical ingredients (APIs), ensuring the precise stereochemistry required for therapeutic efficacy and safety. It is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries engaged in developing and scaling up novel chiral drug candidates.

Application

• Chiral Resolution Agent: Used for the separation of enantiomers in complex synthetic pathways.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of specific, high-value active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis Catalyst/Precursor: Employed in reactions requiring high enantioselectivity to produce single-isomer compounds.
• Reference Standard: Utilized in analytical laboratories for method development and quality control of chiral compounds.
• Academic & Industrial Research: A valuable reagent for exploring new synthetic methodologies in medicinal and organic chemistry.

Basic Information

Product Name	(+)-(10,11-Dihydro-5-Methyl-5H-Dibenzo[A,D]Cyclohepten-5,10-Diyl)Ammonium Hydrogen [S-(R*,R*)]-2,3-Bis(p-Toluoyloxy)Succinate
CAS No.	77099-06-0
Molecular Formula	C42H39NO8
Molecular Weight	685.77 g/mol
Synonyms	(+)-Ammonium (10,11-Dihydro-5-methyl-5H-dibenzo[a,d]cyclohepten-5,10-diyl) hydrogen [S-(R*,R*)]-2,3-bis(4-methylbenzoyloxy)succinate; (R,R)-O,O'-Di-p-toluoyltartaric Acid Ammonium Salt of 10,11-Dihydro-5-methyl-5H-dibenzo[a,d]cyclohepten-5,10-amine; Dihydro-5-methyl-5H-dibenzo[a,d]cyclohepten-5,10-amine (R,R)-O,O'-Di-p-toluoyltartrate; Ammonium hydrogen (R,R)-O,O'-di-p-toluoyltartrate of 5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-amine
EINECS	Contact for details

Quality Control

Our (+)-(10,11-Dihydro-5-Methyl-5H-Dibenzo[A,D]Cyclohepten-5,10-Diyl)Ammonium Hydrogen [S-(R*,R*)]-2,3-Bis(p-Toluoyloxy)Succinate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and chemical assay, to ensure compliance with stringent specifications for pharmaceutical intermediates. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.