Description

Dihydrostreptomycin, [3H(G)] is a tritium-labeled derivative of the aminoglycoside antibiotic dihydrostreptomycin, specifically designed for advanced research applications. This compound matters as a critical radiolabeled tracer for investigating the pharmacokinetics, metabolic pathways, and binding mechanisms of dihydrostreptomycin in biological systems. It is essential for researchers in pharmaceutical development, microbiology, and biochemistry who require precise tracking of this antibiotic's behavior in vitro and in vivo.

Application

• Pharmacokinetic and ADME Studies: Used as a radiolabeled tracer to study the absorption, distribution, metabolism, and excretion (ADME) profile of dihydrostreptomycin in preclinical models.
• Mechanism of Action Research: Enables detailed investigation into the binding interactions and inhibitory mechanisms of dihydrostreptomycin with bacterial ribosomes.
• Metabolic Pathway Tracing: Facilitates the elucidation of metabolic pathways and potential degradation products of the antibiotic in biological matrices.
• Receptor Binding Assays: Serves as a key tool in competitive binding assays and saturation studies to determine binding affinities and receptor densities.
• Quality Control Reference: Can be utilized as an internal standard or reference material in analytical method development for dihydrostreptomycin quantification.
• Environmental Fate Studies: Applied in research to track the environmental persistence and degradation of streptomycin-class antibiotics.

Basic Information

Product Name	Dihydrostreptomycin, [3H(G)]
CAS No.	77093-29-9
Molecular Formula	C21H41N7O12 * (3H)x
Molecular Weight	Contact for details
Synonyms	Tritiated Dihydrostreptomycin; [3H]-Dihydrostreptomycin; Dihydrostreptomycin (tritiated); Dihydrostreptomycin tritiate; Streptomycin dihydro, tritiated; Antibiotic 5-0-2, tritiated; DHSM-[3H]; Dihydrostreptomycin sulfate (tritium-labeled)
EINECS	Contact for details

Quality Control

Our radiolabeled compounds are produced and handled under strict quality protocols to ensure high radiochemical purity and specific activity. Each batch is analyzed to confirm identity and purity, with comprehensive documentation provided. Certificates of Analysis (COA) detailing specific activity, radiochemical purity, analytical method, and solvent information are supplied with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at or below -20°C. This product is strictly light-sensitive (protect from all light exposure). Store only in the original container. Users must handle this material in accordance with all applicable radiation safety regulations and guidelines.

Specification

Item	Specification
Appearance	Solution (color may vary)
Specific Activity	Contact for details
Radiochemical Purity	≥ 95% (by HPLC)
Chemical Purity	Contact for details
Concentration	Contact for details
Solvent	Ethanol/Water or as specified
Identification	Conforms (HPLC, MS)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.