Description

Anisodine Hydrobromide is a synthetic anticholinergic agent derived from tropane alkaloids, primarily valued for its potent muscarinic receptor antagonism. This pharmacological profile makes it a critical intermediate and active pharmaceutical ingredient (API) in the development of treatments for conditions involving excessive cholinergic activity. It is essential for manufacturers and research institutions in the pharmaceutical, biotechnology, and fine chemical sectors focused on neurology and ophthalmology.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced anticholinergic and antispasmodic medications.
• Active Pharmaceutical Ingredient (API): Used in the formulation of ophthalmic solutions for pupil dilation (mydriasis) and cycloplegia.
• Neurological Research: A standard compound for studying muscarinic acetylcholine receptor (mAChR) function and signal transduction pathways in vitro.
• Preclinical Development: Employed in animal models to investigate potential therapies for organophosphate poisoning, motion sickness, and gastrointestinal spasms.
• Reference Standard: Serves as a high-purity calibrant and quality control standard in analytical laboratories for HPLC and LC-MS methods.
• Fine Chemical Synthesis: Utilized as a specialized precursor for creating novel tropane-based derivatives with modified biological activity.

Basic Information

Product Name	Anisodine Hydrobromide
CAS No.	76822-34-9
Molecular Formula	C17H21NO4 • HBr
Molecular Weight	384.27 g/mol
Synonyms	Anisodine HBr; 6β-Hydroxyhyoscyamine Hydrobromide; 3α-Tigloyloxy-6β-hydroxytropane Hydrobromide; AT3 Hydrobromide; Anisodine Bromhydrate; Anisodine Hydrobromidum; (1R,3r,5S,6R)-6-Hydroxy-8-methyl-8-azabicyclo[3.2.1]oct-3-yl (2S)-3-hydroxy-2-phenylpropanoate hydrobromide
EINECS	Contact for details

Quality Control

Our Anisodine Hydrobromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and stringent control of residual solvents and heavy metals. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with cGMP and relevant pharmacopeial guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and potency. For long-term storage, consider desiccants or inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.