Description

(+)-Dipivaloyl-D-Tartaric Acid CAS NO 76769-55-6 is a high-purity chiral resolving agent and a key synthetic intermediate in organic chemistry. Its primary value lies in its exceptional ability to separate enantiomers of amines and other basic compounds, which is critical for producing single-isomer active pharmaceutical ingredients (APIs). This compound is essential for research laboratories and manufacturing facilities in the pharmaceutical, agrochemical, and fine chemical sectors that require precise chiral synthesis and purification.

Application

• Chiral Resolution Agent: Widely used for the preparative separation of enantiomers of racemic amines and amino alcohols via diastereomeric salt formation.
• Pharmaceutical Intermediate: Serves as a crucial building block in the asymmetric synthesis of chiral drugs, including β-blockers and other cardiovascular agents.
• Catalyst and Ligand Precursor: Employed in the synthesis of chiral ligands for asymmetric catalysis, such as in hydrogenation and alkylation reactions.
• Analytical Chemistry: Used as a chiral selector or derivatizing agent in High-Performance Liquid Chromatography (HPLC) for enantiomeric purity analysis.
• Agrochemical Synthesis: A key intermediate in the production of enantiomerically pure herbicides and pesticides.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals, flavors, and fragrances where chiral purity is paramount.

Basic Information

Product Name	(+)-Dipivaloyl-D-Tartaric Acid
CAS No.	76769-55-6
Molecular Formula	C14H22O8
Molecular Weight	318.32 g/mol
Synonyms	(2R,3R)-2,3-Bis(2,2-dimethylpropanoyloxy)succinic acid; D-DTTA; (R,R)-O,O'-Di-pivaloyl tartaric acid; (2R,3R)-Di-O-pivaloyl-L-tartaric acid; (2R,3R)-2,3-Bis(pivaloyloxy)butanedioic acid; (R,R)-Dipivaloyltartaric acid; D-DPTA; (R,R)-Di-p-toluoyltartaric acid analog
EINECS	Contact for details

Quality Control

Our (+)-Dipivaloyl-D-Tartaric Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for chiral synthesis and resolution. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming specifications for identity, assay, enantiomeric excess, and related substances.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	168°C - 172°C
Specific Rotation [α]20/D	+138° to +142° (c=1 in CHCl3)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.