Description

4-Bromoisatoic Anhydride is a specialized brominated derivative of isatoic anhydride, serving as a key synthetic intermediate in advanced organic chemistry. This compound is valued for its reactivity as an electrophile, enabling the efficient introduction of the 4-bromoanthranilic acid scaffold into target molecules. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential drug candidates, particularly those containing quinazolinone or other fused heterocyclic cores.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require a halogenated aromatic moiety.
• Material Science Research: Employed in the creation of novel organic ligands, dyes, or photoactive materials where bromine substitution is necessary for property modulation.
• Academic & Contract Research: Serves as a valuable reagent in university laboratories and CROs (Contract Research Organizations) for methodological studies and library synthesis.
• Fine Chemical Production: Acts as a precursor in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	4-Bromoisatoic Anhydride
CAS No.	76561-16-5
Molecular Formula	C8H4BrNO3
Molecular Weight	242.03 g/mol
Synonyms	4-Bromo-1H-3,1-benzoxazine-2,4(1H)-dione; 4-Bromo-2H-3,1-benzoxazine-2,4(1H)-dione; 4-Bromo-2,4-dihydro-1H-3,1-benzoxazine-2,4-dione; 4-Bromoisatoic acid anhydride; 4-Bromoanthranilic acid cyclic carbamate; 4-Bromo-1,3-dihydro-2H-3,1-benzoxazine-2,4-dione
EINECS	Contact for details

Quality Control

Our 4-Bromoisatoic Anhydride is manufactured under strict quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.